Fig. 2From: CircMED13L_012 promotes lung adenocarcinoma progression by upregulation of MAPK8 mediated by miR-433-3p Influence of circMED13L_012 on the malignant behavior of NSCLC cell lines. a Impact of circMED13L_012 specific shRNAs on expression level of circMED13L_012 and MED13L_012 in A549 tumor cells. b qRT-PCR study of circMED13L_012 and MED13L expression level in A549 tumor cell groups treated by circMED13L_012 overexpression vector and control vector respectively. c–e Tumor survivability test of A549 cell groups transfected by sh-circMED13L_012, circMED13L_012 overexpression vector and control vector respectively. Tumor cells were challenged by docetaxel (c), doxorubicin (d) and gefitinib (e), with different range of concentrations for each chemo-agentBack to article page