Fig. 3

Influence of circMED13L_012 modulation on the proliferative abilities of NSCLC cell lines. a, b Influences of sh-circMED13L_012 or circMED13L_012 overexpression vector transfection on tumor cell proliferation. A549 and NCI-H1299 cells were respectively transfected with sh- circMED13L_012, circMED13L_012 overexpression and control vectors for 1d-5d and CCK8 analysis was performed on each cell group, c, d A549 and NCI-H1299 cells were respectively transfected with sh-circMED13L_012, circMED13L_012 overexpression vector or control vectors, Transwell analysis was performed on each cell group to evaluate the influences of circMED13L_012 overexpression and silencing on the migration and invasion of the tumor cells. e Western Blot analysis on Ki67, E-cadherin, N-Cadherin and vimentin protein expression values in A549 cells transfected by sh-circMED13L_012, circMED13L_012 overexpression vector and control vector respectively, f, g qRT-PCR study on Ki-67, E-Cadherin, N-Cadherin and vimentin mRNA expression values in A549 cells transfected by sh-circMED13L_012, circMED13L_012 overexpression vector and control vector respectively