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Fig. 3 | Cancer Cell International

Fig. 3

From: Circular RNA CDR1as promotes tumor progression by regulating miR-432-5p/E2F3 axis in pancreatic cancer

Fig. 3

MiR-432-5p targets circCDR1as in pancreatic cancer cells. a The predicted binding site of circCDR1as and miR-432-5p by Starbase database. b The relative luciferase activities of wild-type and mutated circCDR1as 3ˊ-UTR luciferase vectors co-transfected with control or miR-432-5p mimics in PANC-1 and ASPC-1 cells. c Relative expression of miR-432-5p in normal tissues and PC tissues. d The relation of circCDR1as expressions and miR-432-5p expressions in PC tissues. e, f The migration and invasion of PANC-1, ASPC-1 cells transfected with NC mimic and miR-432-5p mimic. g, h The proliferation of PANC-1, ASPC-1 cells transfected with NC mimic and miR-432-5p mimic (*p < 0.05, **p < 0.01)

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Cancer Cell International

ISSN: 1475-2867

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