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Fig. 4 | Cancer Cell International

Fig. 4

From: Circular RNA CDR1as promotes tumor progression by regulating miR-432-5p/E2F3 axis in pancreatic cancer

Fig. 4

E2F3 targets miR-432-5p in PANC-1, ASPC-1 cells. a The predicted binding site of miR-432-5p and E2F3 by Starbase database. b The relative luciferase activities of wild-type and mutated E2F3 3′-UTR luciferase vectors co-transfected with control or miR-432-5p mimics in PANC-1 and ASPC-1 cells. c The relationship between the expression of miR-432-5p and E2F3 in pancreatic cancer samples by Starbase database. d The relation between the expression of miR-432-5p and E2F3 in PC samples in this study. e The miR-432-5p mRNA expression in PC cells transfected with NC mimic, miR-432-5p mimic, NC inhibitor, miR-432-5p inhibitor. f, g The E2F3 expression in PANC-1, ASPC-1 cells transfected with NC mimic, miR-432-5p mimic, NC inhibitor, miR-432-5p inhibitor via western blot (*p < 0.05, **p < 0.01)

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