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Fig. 3 | Cancer Cell International

Fig. 3

From: LINC00221 silencing prevents the progression of hepatocellular carcinoma through let-7a-5p-targeted inhibition of MMP11

Fig. 3

Downregulation of LINC00221 restrains migration and invasion of HCC (Huh7 and MHCC97-H) cells. a, b migration distance of Huh7 (a) and MHCC97-H (b) cells assessed by scratch test. c, d number of invaded Huh7 (c) and MHCC97-H (d) cells examined by Transwell assay. e, f Bcl-2, Bax, Cyclin D1, and CDK4 protein expression in Huh7 (e) and MHCC97-H (f) cells measured by Western blot analysis. Cell experiments were independently repeated 3 times. *p < 0.05 vs. the si-NC group; #p < 0.05 vs. the oe-NC group. Comparison among multiple groups was made using one-way ANOVA with Tukey’s post hoc test

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