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Table 2 Univariate and multivariate analyses of prognostic factors for OS in gastric cancer

From: LncRNA HOXA-AS3 promotes gastric cancer progression by regulating miR-29a-3p/LTβR and activating NF-κB signaling

Variable Overall survival
Univariate analysis Multivariate analysis
P value HR (95% CI) P value HR (95% CI)
Age (yr) 0.361 0.705 (0.332–1.494)   
≤ 50 vs > 50
Gender 0.815 1.084 (0.552–2.130)   
 Male vs female
Tumor diameter (cm) 0.002** 2.804 (1.450–5.422) 0.237 1.585 (0.739–3.399)
≤ 4 vs > 4
Tumor location 0.719 0.887 (0.463–1.701)   
 Up + Middle vs Down
Tumor differentiation 0.027* 2.125 (1.091–4.137) 0.144 1.681 (0.838–3.375)
 High + Middle vs Low
CEA (ng/ml) 0.386 1.439 (0.632–3.277)   
  ≤ 5 vs > 5
CA 19–9 (U/ml) 0.843 0.920 (0.404–2.095)   
  ≤ 37 vs > 37
HP infection 0.918 0.967 (0.506–1.846)   
 − vs + 
T stage 0.011* 2.645 (1.245–5.618) 0.385 0.640 (0.234–1.752)
 T1-2 vs T3-4
N stage  < 0.0001**** 5.800 (2.532–13.288) 0.082 2.377 (0.897–6.300)
 N0 vs N1-3
HOXA-AS3 in tissues  < 0.0001**** 6.723 (2.937–15.385) 0.003** 4.662 (1.691–12.856)
 High vs Low
  1. *< 0.05; **< 0.01; ****< 0.0001