Skip to main content

Table 5 Cetuximab resistance-related genes from the Genomics of Drug Sensitivity in Cancer database

From: Identification of key genes involved in tumor immune cell infiltration and cetuximab resistance in colorectal cancer

Cancer feature Effect size p value FDR% No. of altered cell lines Tissue analysis
SRGAP3_mut −1.310 0.0382 99.7 3 COREAD
PBRM1_mut −0.971 0.0791 99.7 4 COREAD
B2M_mut −0.722 0.0879 99.7 7 COREAD
FBXW7_mut −0.575 0.0998 99.7 13 COREAD
BRAF_mut 0.580 0.109 99.7 10 COREAD
cnaCOREAD47 0.737 0.111 99.7 6 COREAD
cnaCOREAD18 0.611 0.124 99.7 8 COREAD
MGA_mut −0.688 0.132 99.7 6 COREAD
cnaCOREAD14 0.892 0.147 99.7 3 COREAD
CTCF_mut −0.560 0.17 99.7 7 COREAD
cnaCOREAD37 0.634 0.172 99.7 6 COREAD
CDH1_mut −0.819 0.195 99.7 3 COREAD
CTNNB1_mut −0.577 0.199 99.7 6 COREAD
CREBBP_mut 0.530 0.213 99.7 6 COREAD
CHD9_mut −0.468 0.231 99.7 9 COREAD
BRWD1_mut −0.740 0.231 99.7 3 COREAD
CHD4_mut 0.518 0.285 99.7 3 COREAD
APC_mut −0.285 0.313 99.7 31 COREAD
AKAP9_mut −0.412 0.316 99.7 8 COREAD
cnaCOREAD32 −0.372 0.347 99.7 6 COREAD