Fig. 5From: TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitinationTRIM47 regulates tumor suppressor protein and oncoprotein and mediate the ubiquitination and degradation of P53 in RCC. a Detection of the expression of anticancer proteins and oncoproteins after TRIM47 overexpression or knockout in 769P cell line. b The stable His-P53 overexpression stable transfected cells and the His-P53 + Flag-TRIM47 overexpression stable transfected cells were constructed and detected by Western blot (left panel). Co-immunoprecipitation was used to detected the interaction of TRIM47 and P53 in the 769P cell line (right panel)Back to article page