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Fig. 5 | Cancer Cell International

Fig. 5

From: TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination

Fig. 5

TRIM47 regulates tumor suppressor protein and oncoprotein and mediate the ubiquitination and degradation of P53 in RCC. a Detection of the expression of anticancer proteins and oncoproteins after TRIM47 overexpression or knockout in 769P cell line. b The stable His-P53 overexpression stable transfected cells and the His-P53 + Flag-TRIM47 overexpression stable transfected cells were constructed and detected by Western blot (left panel). Co-immunoprecipitation was used to detected the interaction of TRIM47 and P53 in the 769P cell line (right panel)

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Cancer Cell International

ISSN: 1475-2867

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