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Fig. 5 | Cancer Cell International

Fig. 5

From: TRIM47 promotes malignant progression of renal cell carcinoma by degrading P53 through ubiquitination

Fig. 5

TRIM47 regulates tumor suppressor protein and oncoprotein and mediate the ubiquitination and degradation of P53 in RCC. Detection of the expression of anticancer proteins and oncoproteins after TRIM47 overexpression or knockout in 769P cell line. b The stable His-P53 overexpression stable transfected cells and the His-P53 + Flag-TRIM47 overexpression stable transfected cells were constructed and detected by Western blot (left panel). Co-immunoprecipitation was used to detected the interaction of TRIM47 and P53 in the 769P cell line (right panel)

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