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Fig. 9 | Cancer Cell International

Fig. 9

From: Systematic analysis of the expression and prognosis relevance of FBXO family reveals the significance of FBXO1 in human breast cancer

Fig. 9

Protein–protein Interaction (PPI) Network and Correlative Analysis of FBXO1. a PPI network of FBXO1 and 108 co-expressed genes. The most significant modules and hub genes of the PPI network were analysed by Cytoscape software, which were marked in yellow. b The hub-genes were identified using cytoHubba tool kits in Cytoscape. c The PPI network of hub-genes were identified using STRING database. d The biological process analysis of hub-genes was performed using the BiNGO plug-in. P < 0.05 was considered to be a statistically significant difference. e The hierarchical clustering of hub-genes was constructed using UCSC online database. f The heat map of correlation between FBXO1 and hub-genes in BC patients analysed by bc-GenExMiner v4.0. Different color represents the percentage of correlationship. 1 stands for complete positive correlation and -1 stands for complete nagetive correlation

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