Fig. 6From: Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancerOverexpression of ABCC5 in mice bearing subcutaneous BC xenografts reduces the antitumor activity of MTA. Tumor size was measured with a caliper (a). The excised tumors were weighed at the end point (b), and data are presented as mean ± SD (n = 6), *p < 0.05. Images of excised tumors from each group are shown (c)Back to article page