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Fig. 5 | Cancer Cell International

Fig. 5

From: CDC42EP3 promotes colorectal cancer through regulating cell proliferation, cell apoptosis and cell migration

Fig. 5

CDC42EP3 inhibited tumor growth of colorectal cancer in vivo. a The measurement of tumor volume started from day 10 post inoculation and ended at day 20 post inoculation. Mice were subjected to in vivo bioluminescent imaging (b), and the bioluminescence intensity was scanned and used to represent the tumor burden (c). d After sacrificing the mice, implanted tumors were removed, photographed, and weighted. e The expression of Ki-67 in tumors was detected by IHC. f The effects of CDC42EP3 knockdown on several cancer-related signaling pathways were estimated by western blotting. The representative images were randomly selected from at least 3 independent experiments in duplicate. *P < 0.05, **P < 0.01, ***P < 0.001

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