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Fig. 3 | Cancer Cell International

Fig. 3

From: LINC01089 functions as a ceRNA for miR-152-3p to inhibit non‐small lung cancer progression through regulating PTEN

Fig. 3

There is a targeting relationship between LINC01089 and miR-152-3p. a It was found that LINC01089 contained a potential binding site for miR-152-3p, which was predicted by StarBase database. b Pearson’s correlation analysis was used to analyze the relationship between LINC01089 and miR-152-3p in NSCLC tissues. c The targeting relationship between LINC01089 and miR-152-3p was validated by dual luciferase reporter assay. NS P > 0.05, ***P < 0.001. d The expression of miR-152-3p in NSCLC cells after overexpression and knockdown of LINC01089 was detected by qRT-PCR. **P < 0.01, ***P < 0.001. e qRT-PCR was used to detect the expression of miR-152-3p in adjacent tissues and NSCLC tissues. ***P < 0.001, f The expression levels of miR-152-3p in normal lung epithelial cell BEAS-2B and NSCLC cell lines were detected by qRT-PCR. *P < 0.05, **P < 0.01

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