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Fig. 5 | Cancer Cell International

Fig. 5

From: LINC01089 functions as a ceRNA for miR-152-3p to inhibit non‐small lung cancer progression through regulating PTEN

Fig. 5

PTEN was a target gene of miR-152-3p. a The potential binding site between miR-152-3p and PTEN 3’UTR predicted by bioinformatics analysis. b Pearson’s correlation analysis of PTEN expression and miR-152-3p expression in NSCLC tissues. c The targeting relationship between PTEN and miR-152-3p was detected by dual luciferase reporter assay, NS P > 0.05, ***P < 0.001. d Western blot was used to detect the expression of PTEN in NSCLC cell lines after transfection of miR-152-3p mimics and inhibitors. e After overexpression and knockdown of LINC01089, the expression of PTEN in NSCLC cells was detected by Western blot

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