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Fig. 6 | Cancer Cell International

Fig. 6

From: LINC01089 functions as a ceRNA for miR-152-3p to inhibit non‐small lung cancer progression through regulating PTEN

Fig. 6

LINC01089 affected the proliferation, migration and invasion of H1299 cells via miR-152-3p/PTEN axis. a-c: After miR-152-3p mimics were transfected into H1299 cells overexpressing LINC01089, the expressions of LINC01089, miR-152-3p and PTEN mRNA were detected by qRT-PCR. NS P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001. d CCK-8 assay was used to detect the proliferation of H1299 cells after transfection of miR-152-3p mimics into H1299 cells overexpressing LINC01089, *P < 0.05, **P < 0.01(vs. Vector); &P < 0.05, &&P < 0.01(vs. LINC01089/NC). e The migration ability of H1299 cells was measured by scratch assay after transfection of miR-152-3p mimics into H1299 cells overexpressing LINC01089, **P < 0.01. f After miR-152-3p mimics were transfected into H1299 cells overexpressing LINC01089, the invasive ability of H1299 cells was detected by Transwell assay. **P < 0.01. g Western blot was used to detect the regulatory effects of LINC01089 and miR-152-3p on the expression of PTEN in NSCLC cell lines

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