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Fig. 8 | Cancer Cell International

Fig. 8

From: MSCs loaded with oncolytic reovirus: migration and in vivo virus delivery potential for evaluating anti-cancer effect in tumor-bearing C57BL/6 mice

Fig. 8

Determination of the splenic IL-6, IFN-γ, IL-10, and TGF-β cytokine secretion in response to stimulators. According to analyzed data, the robust response in the released cytokines level was observed after 3rd treatments. Reovirus had a direct effect on released IFN-γ level and an indirect effect on inflammatory cytokines when accompanying with MSCs its function was moderated. The experiment was performed in triplicate (*: P ≤ 0.05; **: P ≤ 0.01)

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