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Fig. 2 | Cancer Cell International

Fig. 2

From: The loss of DLG2 isoform 7/8, but not isoform 2, is critical in advanced staged neuroblastoma

Fig. 2

Comparison of DLG family member isoforms by stage. DLG1 isoform and total gene expression by NB stage from (a) the NCI TARGET data; phs000218 (RNAseq) and (b) NB patient dataset (GSE16476) (microarray). c DLG2 isoform and total gene expression by NB stage from the NCI TARGET data, (d) total mean expression level of DLG2 isoforms in all NB stages, (e) qPCR data comparing DLG2-isoform 2 and DLG2-isoform 7/8 expression in 22 primary NB tumors. DLG4 isoform and total gene expression by NB stage from (f) the NCI TARGET data; phs000218 (RNAseq) and (g) NB patient dataset (GSE16476) (microarray). h comparison of the relative total DLG expression in the NCI TARGET NB dataset. The expression data are presented as median centred log2 fold change and plotted as Tukeys box and whisker plots showing IQR, line at the median, + at the mean with whiskers ± 1.5-fold of interquartile range. Data outside the whiskers are shown as outliers. *p < 0.05, **p < 0.01, ***p < 0.001

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