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Fig. 7 | Cancer Cell International

Fig. 7

From: Circular RNA circCSPP1 knockdown attenuates doxorubicin resistance and suppresses tumor progression of colorectal cancer via miR-944/FZD7 axis

Fig. 7

CircCSPP1 knockdown suppresses the tumor growth of CRC in vivo. a–d The nude mice were injected with CRC cells with stable expression of sh-NC or sh-circCSPP1 and treated with DOX. a Tumor volume was measured every 7 days to 28 days. b After injection for 28 days, the mice were executed and tumors were weighted. c The expression of circCSPP1, miR-944, and FZD7 in tumors were detected by qRT-PCR assay. d The protein level of FZD7 was detected by western blot assay. d Diagram of circCSPP1 regulated DOX resistance and tumor progression. *P < 0.05

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