Fig. 9From: Combating drug resistance in acute myeloid leukaemia by drug rotations: the effects of quizartinib and pexidartinibDistribution of most common mutation at WT\(_{1/2}\) for FLT3\(^+\)-AML. The relative frequency of each mutation is given for each treatment protocol. The figure was obtained by simulations of the mutational landscape using the wollsey stochastic evolution simulator [6]. The blue line indicates the expected mutation frequency if all mutations were equally likely and equally fitBack to article page