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Fig. 9 | Cancer Cell International

Fig. 9

From: Combating drug resistance in acute myeloid leukaemia by drug rotations: the effects of quizartinib and pexidartinib

Fig. 9

Distribution of most common mutation at WT\(_{1/2}\) for FLT3\(^+\)-AML. The relative frequency of each mutation is given for each treatment protocol. The figure was obtained by simulations of the mutational landscape using the wollsey stochastic evolution simulator [6]. The blue line indicates the expected mutation frequency if all mutations were equally likely and equally fit

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