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Table 3 Inhibitory coefficients of pexidartinib and quizartinib

From: Combating drug resistance in acute myeloid leukaemia by drug rotations: the effects of quizartinib and pexidartinib

  IC50 IC90
MOLM-14 MV4-11 MOLM-14 MV4-11
Quizartinib 0.38 ± 0.17 0.31 ± 0.16   
Pexidartinib 51 ± 4 37 ± 6 160 ± 27 530 ± 48
  1. Values are averages (± standard deviations) in nM