Table 1 CDC27 RNA expression changes in different neoplasms

Gastrointestinal cancers

 Tumoral rectum or colon tissue

Upregulation

CRC progression, patient’s survival

[23]

Breast cancer

 Human breast cancer tissues

Downregulation

Prognostic biomarker

[46]

 Human breast cancer tissues

Upregulation

Potential to explain disease recurrence

[32]

 Negative breast cancer cell lines (TNBC) (MDA-MB-435 and MDA-MB-231)

Downregulation

Radio-responsiveness

[30]

SCC of cervix

 Irradiated SiHa

Downregulation

Radio-responsiveness status and treatment failure

[47]

Glioma

 Human glia cell lines and glioma tissue

Downregulation

Chemoresistancy to β-lap

[29]

Lung cancer

 Lung adenocarcinoma

Upregulation

Cell cycle progression and tumor progression

[82]

 Non-small cell lung carcinoma cell line (EGR1-overexpressing H1299 cells)

Downregulation

Tumor progression

[44]

Bladder cancer (BC)

 Cisplatin sensitive human BC cell line (T24) and cisplatin resistant BC cell line (T24R2)

Upregulation

Metastasis and recurrence of progressive BC

[83]