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Fig. 2 | Cancer Cell International

Fig. 2

From: Discovery and validation of PZP as a novel serum biomarker for screening lung adenocarcinoma in type 2 diabetes mellitus patients

Fig. 2

Identification of unique serum proteins in T2DM patients with LAC. ac Volcano plot showing the DEPs in the T2DM, LAC and T2DM + LAC patients compared to healthy controls. d Venn diagram of the 70 differentially expressed proteins in the serum samples from the four comparisons (T2DM vs. NC, LAC vs. NC and T2DM + LAC vs. NC). In total, 13 proteins were specifically expressed in the T2DM + LAC group. e Hierarchical cluster analysis of the 70 DEPs in the NC, T2DM, LAC, and T2DM + LAC serum samples. Note: There were five samples in each group. Pseudocolors indicate differential expression (red, upregulation; blue, downregulation)

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