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Fig. 1 | Cancer Cell International

Fig. 1

From: Identification of four key prognostic genes and three potential drugs in human papillomavirus negative head and neck squamous cell carcinoma

Fig. 1

DEGs in three datasets from GEO and meta-analysis results. a–c Volcano plots showing the DEGs in GSE40774, GSE55550 and GSE39366, respectively. The red, blue and gray dots indicate genes with upregulated, downregulated, and unchanged expression, respectively, as determined by the thresholds. d Venn diagram showing the overlapping DEGs in the three datasets. e Meta-analysis showed the overlap between the gene lists: the purple curves connect identical genes, and the blue curves connect genes that belong to the same enriched GO term. The inner circle indicates the gene lists, and hits are arranged along the arc. Genes identified as hits in multiple lists are colored in dark orange, and genes unique to a list are colored in light orange. f Heatmap of the top 20 enriched GO terms across DEG lists from the meta-analysis of the three datasets. GO terms are colored by P-value

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