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Fig. 4 | Cancer Cell International

Fig. 4

From: Establishment and characterization of HXWMF-1: the first mouse fibroblastic tumor cell line derived from leukemia-associated fibroblasts

Fig. 4

Tumorigenicity of HXWMF-1 cells. a Subcutaneous tumor mass in nude mice (arrow indicated). b The growth curve of subcutaneous tumors in nude mice (n = 6, age 5–6 weeks). All animal procedures were carried out in accordance with the guidelines established by the internal Institutional Animal Care and Use Committee and Ethics Committee guidelines of Sichuan University. c HE staining of the tumor showed that the tumor mass was composed of leukemia cells and blood vessels (×200 magnification). df, h On IHC staining, tumors derived from HXWMF-1 expressed α-SMA (d), FSP1 (e), Vimentin (f), and HSP47 (h). Original magnification: ×1000

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