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Fig. 4 | Cancer Cell International

Fig. 4

From: LINC00514 upregulates CCDC71L to promote cell proliferation, migration and invasion in triple‐negative breast cancer by sponging miR-6504-5p and miR-3139

Fig. 4

The inhibitive effect of overexpressed miR-6504-5p or miR-3139 on TNBC cell proliferation, migration and invasion. a RT-qPCR of miR-6504-5p and miR-3139 expression in TNBC cells and MCF-10 A cells. b, c The proliferation in TNBC cells with miR-6504-5p/miR-3139 mimics transfection was evaluated through colony formation and EdU assays. d Flow cytometry analysis demonstrated the function of upregulated miR-6504-5p and miR-3139 on cell apoptosis. e, f Bax and Bcl-2 protein levels in TNBC cells with transfection of miR-6504-5p/miR-3139 mimics or NC mimics. g, h Impact of upregulated miR-6504-5p/miR-3139 on TNBC cell migratory ability. i Transwell assay evaluated the invasion in miR-6504-5p/miR-3139 overexpressed cells. *p < 0.05, **p < 0.01, ***p < 0.001

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