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Table 2 Univariate and multivariate analysis of various clinicopathologic characteristics related with overall survival in OSCC patients(n = 303)

From: Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation

  Univariate analysis Multivariate analysis P
HR (95% CI) P HR (95% CI)
Gender 0.924 (0.656–1.300) 0.648   
Age 1.185 (0.853–1.646) 0.311   
cT stage 1.344 (0.951–1.899) 0.094   
cN stage 1.471 (1.060–2.039) 0.021* 1.534 (1.008–2.335) 0.046*
cM stage 0.692 (0.171–2.799) 0.605   
Clinical stage 1.342 (0.923–1.950) 0.123   
Histological grade 1.282 (0.990–1.661) 0.06 1.317 (1.011–1.715) 0.041*
SHMT2 level 1.522 (1.094–2.117) 0.013* 1.452 (1.034–2.037) 0.031*
  1. cT stage clinic T stage, cN stage clinic N stage, cM stage clinic M stage
  2. *represents P < 0.05, **represents P < 0.01, ***represents P < 0.001