Site of tumors | Types of fibroblasts | Functions of fibroblasts | Â |
---|---|---|---|
Prostate | Normal lung fibroblasts | Anti-tumor | [96] |
Normal associated fibroblasts | Anti-tumor | [25] | |
CAFs | Tumor-promoting | ||
Fibroblasts from benign hyperplasia | Anti-tumor | [26] | |
Skin | Normal dermal fibroblasts | Anti-tumor | [16] |
Senescent fibroblasts | Tumor-promoting | ||
Pancreas | CAFs | Anti-tumor | |
Stomach | CAFs | Tumor-promoting | [46] |
Breast | CAFs | Pro-inflammation | [48] |
Chemoresistance | [61] | ||
Ovary | CAFs | Tumor-promoting | [48] |
Lung | CAFs | Tumor-promoting | [51] |
Colon | CAFs | Chemoresistance | [54] |
Liver | CAFs | Pro-angiogenesis | [57] |