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Table 1 Functions of fibroblasts based on site of tumors

From: Fibroblasts in cancer dormancy: foe or friend?

Site of tumors

Types of fibroblasts

Functions of fibroblasts

 

Prostate

Normal lung fibroblasts

Anti-tumor

[96]

Normal associated fibroblasts

Anti-tumor

[25]

CAFs

Tumor-promoting

[25, 41]

Fibroblasts from benign hyperplasia

Anti-tumor

[26]

Skin

Normal dermal fibroblasts

Anti-tumor

[16]

Senescent fibroblasts

Tumor-promoting

[82, 83]

Pancreas

CAFs

Anti-tumor

[15, 31]

Stomach

CAFs

Tumor-promoting

[46]

Breast

CAFs

Pro-inflammation

[48]

Chemoresistance

[61]

Ovary

CAFs

Tumor-promoting

[48]

Lung

CAFs

Tumor-promoting

[51]

Colon

CAFs

Chemoresistance

[54]

Liver

CAFs

Pro-angiogenesis

[57]