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Fig. 7 | Cancer Cell International

Fig. 7

From: Circ_0000745 strengthens the expression of CCND1 by functioning as miR-488 sponge and interacting with HuR binding protein to facilitate the development of oral squamous cell carcinoma

Fig. 7

CCND1 knockdown inhibited OSCC cell growth. a The efficiency of CCND1 knockdown was checked by qPCR. In Cal-27 and SCC9 cells transfected with si-CCND1 or si-NC, cell proliferation was assessed by (b) CCK-8 assay and (c) colony formation assay. d Cell apoptosis and (e) cell cycle distribution were investigated by flow cytometry assay. f, g The protein levels of PCNA and Cleaved-caspase 3 in these transfected cells were quantified by western blot. **P < 0.01 and ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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