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Fig. 3 | Cancer Cell International

Fig. 3

From: Targeting a novel LncRNA SNHG15/miR-451/c-Myc signaling cascade is effective to hamper the pathogenesis of breast cancer (BC) in vitro and in vivo

Fig. 3

LncRNA SNHG15 promoted malignant phenotypes in BC cells. a, b CCK-8 assay was performed to determine cell proliferation abilities. c, d Colony formation assay was used to examine colonies formation abilities in BC cells. e, f Knock-down of LncRNA SNHG15 promoted cell apoptosis in BC cells, which were determined by using Annexin V-FITC/PI double staining method. g The expression levels of N-cadherin were monitored by using the Western Blot analysis. h Cell invasion and (i) migration were detected by transwell assay and wound scratch assay, respectively. Each experiment repeated at least 3 times, and *P < 0.05 indicated statistical significance

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