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Fig. 5 | Cancer Cell International

Fig. 5

From: RETRACTED ARTICLE: Targeting a novel LncRNA SNHG15/miR-451/c-Myc signaling cascade is effective to hamper the pathogenesis of breast cancer (BC) in vitro and in vivo

Fig. 5

Knock-down of LncRNA SNHG15 inhibited BC progression in vitro and in vivo by targeting miR-451 and c-Myc. a, b Cell proliferation was evaluated by using the CCK-8 assay. c, d Colony formation abilities were measured by conducting the colony formation assay. e, f Annexin V-FITC/PI double staining assay results suggested that silencing of LncRNA SNHG15 promoted cell apoptosis in BC cells by targeting miR-451 and c-Myc. g Western Blot analysis was used to detect N-cadherin expressions to determine EMT in BC cells. Each experiment repeated at least 3 times, and *P < 0.05 indicated statistical significance

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Cancer Cell International

ISSN: 1475-2867

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