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Fig. 1 | Cancer Cell International

Fig. 1

From: Down-regulation of cylindromatosis protein phosphorylation by BTK inhibitor promotes apoptosis of non-GCB-diffuse large B-cell lymphoma

Fig. 1

CYLD was highly phosphorylated along with BTK phosphorylated in non-GCB-DLBCL. a Protein was extracted from five non-GCB-DLBCL patients (P1–P5) intranodal samples, five lymphadenitis patients inflammatory hyperplasia lymph node samples (B1–B5) as control, blotted sequentially for phospho-CYLD (ser418)/CYLD, phospho-BTK (Tyr223)/BTK, and GAPDH as a loading control. b Protein was extracted from non-GCB-DLBCL cell lines OCI-Ly10 and HBL-1, the human peripheral blood B lymphocyte cell line RPMI 1788 and Jurkat T-cell subclone 3T8 as control, and blotting sequentially for phospho-CYLD (ser418)/CYLD, phospho-BTK (Tyr223)/BTK, and GAPDH as a loading control

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