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Table 1 Clinical characteristics of five DLBCL patients

From: Down-regulation of cylindromatosis protein phosphorylation by BTK inhibitor promotes apoptosis of non-GCB-diffuse large B-cell lymphoma

No. Patient ID COO IHC Immunophenotype FISH IPI scorea Ann Arbor stageb
DLBCL1 D653661 Non-GCB CD20 + , CD10 −, BCL6 + , MUM1 + , BCL2 +  IGH, BCL6 and MYC not rearranged, 3 copies of BCL6 noted indicating trisomy 3q, TP53 deleted 4 III
DLBCL2 D910596 Non-GCB CD20 + , CD10 −, BCL6-, MUM1 + , BCL2 +  IGH, BCL6 and MYC not rearranged, one copy of IGH deleted, TP53 deleted 4 III
DLBCL3 D836558 Non-GCB CD20 + , CD10 −, BCL6-, MUM1 + , BCL2 +  IGH and BCL6 rearranged, TP53 deleted 5 IV
DLBCL4 D982560 Non-GCB CD20 + , CD10 −, BCL6 −, MUM1 −, BCL2- IGH, BCL6 and MYC not rearranged, TP53 deleted 4 III
DLBCL5 D987446 Non-GCB CD20 + , CD10 −, Bcl-6 + , MUM1 + , BCL2 +  IGH and BCL6 rearranged, BCL2 or MYC not rearrangment, TP53 deletion 3 III
  1. aIPI score, International Prognostic Index score
  2. bAnn Arbor stage according to Ann Arbor-Cotswald staging (1989)