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Fig. 1 | Cancer Cell International

Fig. 1

From: Role of tumor mutation burden-related signatures in the prognosis and immune microenvironment of pancreatic ductal adenocarcinoma

Fig. 1

Survival comparison and differentially expressed genes between the TMB_high and TMB_low groups. a PDAC patients were divided into TMB_high and TMB_low groups based on the median TMB scores. b No obvious differences were detected between the TMB_high and TMB_low groups in terms of OS before tumor purity adjustment. c Patients with lower TMB had prolonged OS after adjustment for tumor purity. d A total of 718 differentially expressed genes were identified between the TMB_high and TMB_low groups (LogFC > 2 and FDR < 0.05). e KEGG analysis revealed the potential functions of the differentially expressed genes. Gene ratio refers to the percentage of genes of a specific pathway in TRGs. The size of round symbols refers to the counts of enriched genes. f GSEA revealed the potential functions of the differentially expressed genes

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Cancer Cell International

ISSN: 1475-2867

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