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Table2 Characteristics of patients according to CFP score

From: High CFP score indicates poor prognosis and chemoradiotherapy response in LARC patients

Variables Low CFP group High CFP group p value
Gender 0.729
 Male 68 (71.6) 32 (74.4)  
 Female 27 (28.4) 11 (25.6)  
Age, years [median (CI)] 60 (58–63) 60 (56–64) 0.899
Site 0.076
 Low 35 (36.8) 8 (18.6)  
 Middle 46 (48.4) 28 (67.4)  
 Upper 14 (14.7) 6 (14.0)  
Tumor size 0.002
  > 5 cm 35 (36.8) 28 (65.1)  
  ≤ 5 cm 60 (63.2) 15 (34.9)  
ypTNM category  < 0.001
 0-I 62 (65.3) 12 (27.9)  
 II-III 33 (34.7) 31 (72.1)  
Histopathology (N = 129) 0.335
 Well differentiation 5 (5.8) 1 (2.3)  
 Moderate differentiation 74 (86.0) 35 (81.4)  
 Poor differentiation 7 (8.1) 7 (16.3)  
LNH 8.3 (7.3–9.4) 10.0 (8.6–11.5) 0.051
LVI 0.428
 Positive 4 (4.2) 4 (9.3)  
 Negative 91 (95.8) 39 (90.7)  
PNI  < 0.001
 Positve 5 (5.3) 12 (27.9)  
 Negative 90 (94.7) 31 (72.1)  
Tumor deposits 0.148
 Positive 11 (11.6) 9 (20.9)  
 Negative 84 (88.4) 34 (79.1)  
TRG 0.001
 0–1 64 (67.4) 16 (37.2)  
 2–3 31(32.6) 27 (62.8)  
CEA [median (CI)] 2.6 (2.4–2.9) 5.3 (3.9–7.1) 0.002
FARI, % [median(CI)] 7.0 (6.8–7.3) 9.3 (8.7–9.9)  < 0.001
PNI [median (CI)] 47.4 (46.8–48.0) 42.5 (41.4–43.5)  < 0.001
  1. CI confidence interval, LNH lymph node harvest, LVI lymphovascular invasion, PNI perineural invasion, TRG tumor regression grade, CEA carcinoembryonic antigen, FARI Fibrinogen–Albumin Ratio Index, PNI prognostic nutritional index