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Table2 Characteristics of patients according to CFP score

From: High CFP score indicates poor prognosis and chemoradiotherapy response in LARC patients

Variables

Low CFP group

High CFP group

p value

Gender

0.729

 Male

68 (71.6)

32 (74.4)

 

 Female

27 (28.4)

11 (25.6)

 

Age, years [median (CI)]

60 (58–63)

60 (56–64)

0.899

Site

0.076

 Low

35 (36.8)

8 (18.6)

 

 Middle

46 (48.4)

28 (67.4)

 

 Upper

14 (14.7)

6 (14.0)

 

Tumor size

0.002

  > 5 cm

35 (36.8)

28 (65.1)

 

  ≤ 5 cm

60 (63.2)

15 (34.9)

 

ypTNM category

 < 0.001

 0-I

62 (65.3)

12 (27.9)

 

 II-III

33 (34.7)

31 (72.1)

 

Histopathology (N = 129)

0.335

 Well differentiation

5 (5.8)

1 (2.3)

 

 Moderate differentiation

74 (86.0)

35 (81.4)

 

 Poor differentiation

7 (8.1)

7 (16.3)

 

LNH

8.3 (7.3–9.4)

10.0 (8.6–11.5)

0.051

LVI

0.428

 Positive

4 (4.2)

4 (9.3)

 

 Negative

91 (95.8)

39 (90.7)

 

PNI

 < 0.001

 Positve

5 (5.3)

12 (27.9)

 

 Negative

90 (94.7)

31 (72.1)

 

Tumor deposits

0.148

 Positive

11 (11.6)

9 (20.9)

 

 Negative

84 (88.4)

34 (79.1)

 

TRG

0.001

 0–1

64 (67.4)

16 (37.2)

 

 2–3

31(32.6)

27 (62.8)

 

CEA [median (CI)]

2.6 (2.4–2.9)

5.3 (3.9–7.1)

0.002

FARI, % [median(CI)]

7.0 (6.8–7.3)

9.3 (8.7–9.9)

 < 0.001

PNI [median (CI)]

47.4 (46.8–48.0)

42.5 (41.4–43.5)

 < 0.001

  1. CI confidence interval, LNH lymph node harvest, LVI lymphovascular invasion, PNI perineural invasion, TRG tumor regression grade, CEA carcinoembryonic antigen, FARI Fibrinogen–Albumin Ratio Index, PNI prognostic nutritional index