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Fig. 1 | Cancer Cell International

Fig. 1

From: The effect of miR-539 regulating TRIAP1 on the apoptosis, proliferation, migration and invasion of osteosarcoma cells

Fig. 1

Restoration of miR-539 inhibited cell proliferation and promoted cell apoptosis in 143b and MG63 cells. a The data show that the expression of miR-539 was much lower in osteosarcoma cell lines (143b, MG63) than in an osteoblastic cell line. b The data show that the expression of miR-539 in the miR-539 mimics group (both 143b and MG63) was much higher than that in the miR-539 mimic-NC group and that the difference between the two groups was statistically significant (P < 0.01). c The cell proliferation of 143b osteosarcoma cells. d The cell proliferation of MG63 osteosarcoma cells. The pictures in c and d show that the cell proliferation in the miR-539 mimic groups was much lower than that in the miR-539 mimic-NC groups (P < 0.01). e–f Apoptosis of osteosarcoma 143b cells. g–h Apoptosis of osteosarcoma MG63 cells. All of the above pictures show that the miR-539 mimic groups had higher rates of apoptosis than the miR-539 mimic-NC groups in both the 143b and MG63 osteosarcoma cell lines (P < 0.01)

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