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Fig. 3 | Cancer Cell International

Fig. 3

From: The effect of miR-539 regulating TRIAP1 on the apoptosis, proliferation, migration and invasion of osteosarcoma cells

Fig. 3

TRIAP1 was targeted by miR-539. Effect of miR-539 on the target gene (TRIAP1) expression. a The predicted binding sites of miR-539 and TRIAP1. b Expression level of TRIAP1 after transfection of miR-539 mimics or miR-539 mimics NC. The expression of TRIAP1 in 143b was significantly decreased after transfection with miR-539, indicating that miR-539 might inhibit the proliferation and growth of osteosarcoma cells by regulating the expression of the TRIAP1 gene. c–h The results of western blotting show that the expression of p53, p21, apaf1 and caspase9 was increased while the expression of TRIAP1 was decreased in 143b and MG63 cells transfected with miR-539 mimics

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Cancer Cell International

ISSN: 1475-2867

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