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Fig. 9 | Cancer Cell International

Fig. 9

From: Influence of icariin on inflammation, apoptosis, invasion, and tumor immunity in cervical cancer by reducing the TLR4/MyD88/NF-κB and Wnt/β-catenin pathways

Fig. 9

Effects of ICA on the migration, invasion, and apoptosis of SiHa cells. a CCK-8 assays were performed to demonstrate cell viability in ICA-treated SiHa cells. b Transwell assays were performed to examine the effects of ICA on SiHa cells migration and invasion. c SiHa cell apoptosis was determined by flow cytometer analysis after ICA treatment. d The expression levels of immunosuppressive factors were determined by ELISA assay. e Western blotting was performed to detect the expression levels of TLR4, MyD88, NF-κB p65, Wnt 1 β-catenin, P16, P53, Ki67, Survivin, Bax, Bcl-2, c-Myc, E-cadherin, and Vimentin in ICA-treated SiHa cells. Data are expressed as the mean ± SD. *P < 0.05; **P < 0.01 vs control group

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