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Table 1 Relationship between miR-665 expression and clinicopathological parameters in LUSC patients (n = 69)

From: MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC

Parameter All patients miR-665 expression p value
High (n = 56) Low (n = 13)
Sex 0.726
 Male 57 46 11  
 Female 12 10 2  
Age (years) 0.805
 ≥ 60 25 20 5  
 < 60 44 36 8  
Smoke 0.561
 No 42 35 7  
 Yes 27 21 6  
Differentiation 0.013*
 Moderate–poor 43 39 4  
 Well 26 17 9  
Metastasis 0.237
 Yes 49 41 8  
 No 20 15 5  
Tumor size (cm) 0.001*
 ≥ 3 50 47 3  
 < 3 19 9 10  
TNM stage 0.039*
 I + II 32 23 9  
 III + IV 37 33 4  
  1. The cut-off value of miR-665 was 1.52. *p < 0.01