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Table 1 Relationship between miR-665 expression and clinicopathological parameters in LUSC patients (n = 69)

From: MicroRNA-665 facilitates cell proliferation and represses apoptosis through modulating Wnt5a/β-Catenin and Caspase-3 signaling pathways by targeting TRIM8 in LUSC

Parameter

All patients

miR-665 expression

p value

High (n = 56)

Low (n = 13)

Sex

0.726

 Male

57

46

11

 

 Female

12

10

2

 

Age (years)

0.805

 ≥ 60

25

20

5

 

 < 60

44

36

8

 

Smoke

0.561

 No

42

35

7

 

 Yes

27

21

6

 

Differentiation

0.013*

 Moderate–poor

43

39

4

 

 Well

26

17

9

 

Metastasis

0.237

 Yes

49

41

8

 

 No

20

15

5

 

Tumor size (cm)

0.001*

 ≥ 3

50

47

3

 

 < 3

19

9

10

 

TNM stage

0.039*

 I + II

32

23

9

 

 III + IV

37

33

4

 
  1. The cut-off value of miR-665 was 1.52. *p < 0.01