Fig. 1

Correlation between lncRNA-APOC1P1-3 and breast cancer. a The lncRNA-APOC1P1-3 expression in breast cancer cells (T47D, MCF-7, MDA-MB-231) and normal mammary epithelial cells (MCF-10A) (real time-PCR). n = 3, relative to the control group**P < 0.01. b LncRNA-APOC1P1-3 expressed in both cytoplasm and nuclear compartments in MDA-MB-231 cells (real time-PCR). U6 and U2 RNA were used for nuclear gene expression; and GAPDH and β-actin RNA were for cytoplasmic gene expression. c The overall survival rate of breast cancer patients. Red line, high expression of APOC1P1-3 (110 months), blue line, low expression of APOC1P1-3 (300 months) (n = 816, P < 0.01). d The expression of lncRNA-APOC1P1-3 in 24 fresh breast cancer tissues (RT-PCR). e APOC1P1-3 promotes lung metastasis. (i) The number of lung metastases after tail vein injection with MDA-MB-231 cells infected with APOC1P1-3-knock-down or control vector. (ii) Representative Hematoxylin and Eosin stain (H&E) of lung metastases. Scale bars: above picture is 200 μm, below picture is 50 μm. **, P < 0.01