Fig. 5
From: lncRNA APOC1P1-3 promoting anoikis-resistance of breast cancer cells
Effects of LncRNA- APOC1P1-3 and miRNA-188-3p on the expression of Bcl-2. a, b The down-regulation of miRNA-188-3p in breast cancer cells promotes Bcl-2 gene expression, but overexpression of miRNA-188-3p decreases the Bcl-2 gene expression; c Overexpression of lncRNA- APOC1P1-3 increases the expression of Bcl-2. d Overexpression of lncRNA- APOC1P1-3 followed by up-regulation of miRNA-188-3p abolished the lncRNA- APOC1P1-3 effect on Bcl-2. e, f In four groups (sense + /mimics-, sense-/mimics + , sense + /mimics + , sense-/mimics-) simultaneous transfection of sense and mimics reversed the expression of Bcl-2 when separately transfected with sense/mimics