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Fig. 4 | Cancer Cell International

Fig. 4

From: Bioinformatic analysis identifying FGF1 gene as a new prognostic indicator in clear cell Renal Cell Carcinoma

Fig. 4

Aberrant FGF1 loss of expression in ccRCC comparing to normal renal tissues. a Top 30 genes in the PPI network with high connectivity with surrounding genes (higher color represents stronger connectivity). b The top 30 genes in the PPI network with high connectivity with surrounding genes listed in descending order. (* FGF1 gene is 23rd of the 30 top genes). c Expression of FGF1 in different types of human cancers revealed by Oncomine analysis. Different colored squares indicated the numbers of datasets with FGF1 mRNA over-expressed (red) or down-expressed (blue) in cancer vs. normal tissue. d Aberrant loss of expression of FGF1 in ccRCC comparing to normal renal tissues revealed by GEPIA analysis. e Expression of FGF1 in different types of human cancers by GEPIA analysis (*FGF1 expression in KIRC which is short kidney renal clear cell carcinoma, another name of ccRCC). f Expression of FGF1 in different cancer cell lines

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