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Table 2 Biological Process events centered on FGF1

From: Bioinformatic analysis identifying FGF1 gene as a new prognostic indicator in clear cell Renal Cell Carcinoma

Description

Counts

Background gene counts

FDR

Matching proteins in the network

1-Phosphatidylinositol-3-kinase activity

18

44

2.42e−36

FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, FGFR4, FGF19, FGF8, FGF3, FGFR3, KL, FGF9, GRB2, FGFR1, FGFR2, FRS2, FGF1

Phosphatidylinositol-4,5- bisphosphate 3-kinase activity

18

68

6.57e−34

FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, FGFR4, FGF19,FGF8, FGF3, FGFR3, KL, FGF9, GRB2, FGFR1, FGFR2, FRS2, FGF1

Ras guanyl-nucleotide exchange factor activity

18

243

3.91e−25

FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, FGFR4, FGF19, FGF8, FGF3, FGFR3, KL, FGF9, GRB2, FGFR1, FGFR2, FRS2, FGF1

Protein tyrosine kinase activity

17

180

3.34e−25

FGF4 ,FGF20 ,FGF23, FGF2, FGF10, FGF7, NTRK2, FGFR4, FGF8, FGF3, FGFR3, FGF9, GRB2, FGFR1, FGFR2, NTRK1, FGF1

Growth factor receptor binding

14

131

3.40e−21

FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, FGF19, FGF8, FGF3, KL, FGF9, GRB2, FRS2, FGF1

Fibroblast growth factor receptor binding

13

27

7.40e−27

FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, FGF19, FGF8, FGF3, KL, FGF9, FRS2, FGF1

Transmembrane receptor protein tyrosine kinase activity

6

61

4.88e−09

NTRK2, FGFR4, FGFR3, FGFR1, FGFR2, NTRK1