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Table 3 KEGG signaling pathways centered on FGF1

From: Bioinformatic analysis identifying FGF1 gene as a new prognostic indicator in clear cell Renal Cell Carcinoma

Term description Counts Background gene counts FDR Matching proteins in the network
Ras signaling pathway 19 228 4.33e−27 FGF4, FGF20, FGF23, PLCG1, FGF2, FGF10, FGF7, NTRK2, FGFR4, FGF19, FGF8, FGF3, FGFR3, FGF9, GRB2, FGFR1, FGFR2, NTRK1, FGF1
MAPK signaling pathway 18 293 1.85e−23 FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, NTRK2, FGFR4, FGF19, FGF8, FGF3, FGFR3, FGF9, GRB2, FGFR1, FGFR2, NTRK1, FGF1
PI3K-AKT signaling pathway 18 348 2.42e−22 FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, NTRK2, FGFR4, FGF19, FGF8, FGF3, FGFR3, FGF9, GRB2, FGFR1, FGFR2, NTRK1, FGF1
Regulation of actin cytoskeleton 15 205 1.56e−20 FGF4, FGF20, FGF23, FGF2, FGF10, FGF7, FGFR4, FGF19, FGF8, FGF3, FGFR3, FGF9, FGFR1, FGFR2, FGF1
Signaling pathways regulating pluripotency of stem cells 6 138 7.10e−7 FGF2, FGFR4, FGFR3, GRB2, FGFR1, FGFR2
EGFR tyrosine kinase inhibitor resistance 5 78 1.36e−6 PLCG1, FGF2, FGFR3, GRB2, FGFR2
Insulin secretion 3 84 0.0019 STX1A, SNAP25, VAMP2