Fig. 1
From: Alkaline phosphatase downregulation promotes lung adenocarcinoma metastasis via the c-Myc/RhoA axis
Alkaline phosphatase (ALPL) is downregulated in LUAD. a ALPL mRNA expression was analyzed in the 58 paired LUAD cases in the Cancer Genome Atlas (TCGA). b ALPL mRNA expression was analyzed in 36 paired fresh clinical LUAD tissues. c Western blot analysis of total protein lysates prepared from 36 paired fresh clinical LUAD tissues. Then perform grayscale analysis and statistics. d The relationship between ALPL expression in LUAD patients in the TCGA database and the disease-free survival rate. e Western blot analysis of ALPL protein levels in LUAD cell lines. GAPDH was used as an internal control. All results were presented as the mean ± SD and analyzed by Student’s t-test. The survival curve was analyzed by log-rank test. Asterisks (*) represent statistical significance (P < 0.05)