Table 1 miRNAs that inhibit angiogenesis in CRC

MiR-107

HIF-1β

[74]

MiR-1249

VEGFA/HMGA2

[76]

MiR-125a-3p

PI3K/AKT

[57]

MiR-126

VEGF

[53]

MIR-1299

STAT3

[81]

MiR-143

PI3K/AKT/HIF-1α/VEGF

[61]

MiR-145

p70S6K1/HIF-1α/VEGF

[69]

MiR-148a

pERK/HIF-1α

[72]

MiR-15-16

c-Myc/Max/HIF-2α/FGF2

[105]

MiR-181a-5p

MMP-14

[109]

MiR-19a

KRAS

[97]

MiR-193a-3P

PLAU

[93]

MiR-206

Met/ERK/Elk-1/HIF-1α/VEGF-A

[71]

MiR-216b

HMGB1

[79]

MiR-27b

VEGFC

[54]

MiR-33a

ST8SIA1

[64]

MiR-375

CTGF/EGFR

[87]

MiR-520a

VEGFA

[51]

MiR-590-5p

VEGFA

[45]

MiR-622

CXCR4-VEGFA

[42]

MiR-6868-5p

FOXM1/IL-8

[101]

MiR-7

EGFR/ERK

[84]

MiR-885-3p

BMP/Smad/Id1

[104]