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Fig. 3 | Cancer Cell International

Fig. 3

From: Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma

Fig. 3

CPH treatment altered total acetylation of H3K27 and mono-methylation of H3K4. a Western blot showing the effect of CPH on the total level of active enhancer mark, H3K27Ac and H3K4me1 in BFTC905 and J82 cells for 24 h. DMSO-treated cells was used as vehicle control, and Lamin (A/C) was used as loading control. b The expression of various histone modifiers in BFTC905 cells before and after CPH treatment by RNA seq analysis. Original gel image of (a) can be found in Additional file 3

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Cancer Cell International

ISSN: 1475-2867

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