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Table 2 Univariate Cox regression analysis of OS and DFS in the primary cohort

From: A nomogram for predicting survival of head and neck mucosal melanoma

Variable OS DFS
HR (95% CI) P HR (95% CI) P
Gender
 Male Reference   Reference  
 Female 0.964 (0.717–1.297) 0.811 1.051 (0.766–1.442) 0.759
Age (years old)
 < 60 Reference   Reference  
 ≥ 60 1.246 (0.934–1.660) 0.134 1.203 (0.881–1.644) 0.245
Smoking
 No Reference   Reference  
 Yes 1.020 (0.747–1.395) 0.899 0.787 (0.591–1.049) 0.102
Primary site
 Others Reference   Reference  
 Nasal cavity 2.127 (1.256–3.603) 0.005** 1.510 (0.996–2.288) 0.052
 Paranasal sinus 6.113 (3.101–12.052)  < 0.001*** 3.066 (1.733–5.425)  < 0.001***
 Oral cavity 2.586 (1.465–4.564) 0.001** 2.217 (1.413–3.479) 0.001**
8th T stage
 T3 Reference   Reference  
 T4a 2.801 (1.968–3.989)  < 0.001*** 2.150(1.596–2.896)  < 0.001***
 T4b 11.025(7.301–16.647)  < 0.001*** 6.179 (4.227–9.034)  < 0.001***
8th N stage
 N0 Reference   Reference  
 N1 1.542 (1.113–2.237) 0.009** 1.637 (1.223–2.191) 0.001**
Surgery
 No Reference   Reference  
 Yes 0.707 (0.409–1.220) 0.212 0.612 (0.386–0.969) 0.036*
Radiotherapy
 No Reference   Reference  
 Yes 1.178 (0.879–1.580) 0.273 1.070 (0.828–1.383) 0.603
Chemotherapy
 No Reference   Reference  
 Yes 0.863 (0.647–1.151) 0.317 1.022 (0.792–1.318) 0.869
Immunologic/targeted therapy
 No Reference   Reference  
 Yes 0.694 (0.495–0.974) 0.035* 0.873 (0.657–1.159) 0.348
  1. Cox proportional hazard model was used to conduct Cox regression analysis. * p value < 0.05; ** p value < 0.01; ** p value < 0.001