Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migration

Fig. 6

Exploration of mechanism underlying PSMC2-induced regulation of prostate cancer. a The expression levels of Akt, p-Akt, CDK6, Cyclin D1 and P21 detected by western blotting in PC-3 cells of shCtrl and shPSMC2 groups. b The expression levels of Akt, p-Akt, CDK6, Cyclin D1 and P21 detected by western blotting in PC-3 cells of Control and PSMC2 overexpression groups with or without treatment of MK-2206 (500 nM). c MTT assay was performed to assess the cell proliferation rate of PC-3 cells of Control and PSMC2 overexpression groups with or without treatment of MK-2206 (500 nM). Results were presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page