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Table 3 Univariate and multivariate analyses of factors associated with overall survival in LUADs using Cox regression

From: NEIL3 may act as a potential prognostic biomarker for lung adenocarcinoma

Variable

Univariate

Multivariate

HR (95% CI)

P

HR (95% CI)

P

Age

1.004 (0.985 to 1.023)

0.707

1.016 (0.996 to 1.037)

0.112

Gender

1.105 (0.753 to 1.621)

0.611

1.050 (0.712 to 1.549)

0.806

TNM stage

1.322 (1.202 to 1.454)

0.000*

1.305 (1.021 to 1.669)

0.034*

Tumor stage

1.696 (1.348 to 2.134)

0.000*

1.173 (0.875 to 1.573)

0.286

Metastasis stage

1.594 (0.871 to 2.918)

0.13

0.528 (0.181 to 1.537)

0.241

Node stage

1.820 (1.474 to 2.247)

0.000*

1.180 (0.836 to 1.666)

0.345

NEIL3

1.760 (1.456 to 2.129)

0.000*

1.638 (1.338 to 2.005)

0.000*

  1. *Statistically significant