Skip to main content

Table 2 Effects of death risk factors on breast cancer by univariate analysis (N = 137)

From: SCUBE3 serves as an independent poor prognostic factor in breast cancer

Variable Total HR (95% CI) P-value
SCUBE3    
 Low 106 (77.4%) Reference  
 High 31 (22.6%) 2.77 (1.32, 5.80) 0.0070
Age, years 55.89 ± 11.73 1.05 (1.02, 1.08) 0.0025
Histologic grade    
 2 95 (69.3%) Reference  
 3 42 (30.7%) 2.14 (1.03, 4.44) 0.0422
Histologic type    
 Invasive ductal 114 (83.2%) Reference  
 Other 23 (16.8%) 1.24(0.50, 3.03) 0.6445
Tumor size, cm    0.2435
  ≤ 2 55 (40.1%) Reference  
  > 2 82 (59.9%) 1.28 (0.56, 2.74) 0.5329
Lymph node metastasis    
 Negative 72 (52.6%) Reference  
 Positive 65 (47.4%) 2.73 (1.24, 6.00) 0.0123
TMN stage    
 I 39 (28.5%) Reference  
 II 52 (37.9%) 2.45 (0.66, 9.05) 0.1789
 III 46 (33.6%) 5.70 (1.67, 19.46) 0.0055
ER    
 Negative 41 (30.6%) Reference  
 Positive 93 (69.4%) 0.32 (0.15, 0.67) 0.0023
 Missing 2 1 1
PR    
 Negative 45 (33.1%) Reference  
 Positive 91 (66.9%) 0.73 (0.35, 1.51) 0.0395
 Missing 1 - 1
HER2    
 Negative 100 (80.6%) Reference  
 Positive 24 (19.4%) 1.22 (0.49, 3.04) 0.6676
 Missing 13 11 2
E-cadherin    
 Negative 45 (38.1%) Reference  
 Positive 73 (61.9%) 0.9 (0.43, 1.89) 0.7886
 Missing 19 14 5
TNBC    
 No 108 (82.4%) Reference  
 Yes 23 (17.6%) 2.61 (1.17, 5.81) 0.0189
 Missing 6 4 2
  1. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor
  2. TMN stage was according to the seventh edition of the Guidelines for the American Journal of Critical Care. Variables are expressed as n (%)