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Fig. 1 | Cancer Cell International

Fig. 1

From: Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo

Fig. 1

MCM8 was up-regulated in bladder cancer and MCM8 knockdown cell model was constructed. a The expression levels of MCM8 in bladder cancer tumor tissues and para-carcinoma tissues were determined by immunohistochemical staining. b Kaplan–Meier survival analysis was performed to reveal the relationship between MCM8 expression and prognosis of bladder cancer patients. c The knockdown efficiencies of MCM8 in shMCM8 group were detected by qRT-PCR. d The fluorescence expression in cells was observed after 72 h-transfection. Magnification times: 200×. e The MCM8 mRNA expression in bladder cancer cell lines after transfection was analyzed by qRT-PCR. f The expression of MCM8 protein in bladder cancer cell lines after transfection was detected by western blot. Results were presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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